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Did you mean tga and bone (421 results)?
Association of rs2862851 in TGFA Gene with Peripheral TGFA Levels and the Severity of Knee Osteoarthritis in the Han Chinese Population.
Cui G, Liu D, Wei R, Wu J, Liu R, Wang K. Cui G, et al. Genet Test Mol Biomarkers. 2020 Dec;24(12):771-776. doi: 10.1089/gtmb.2020.0119. Epub 2020 Nov 12. Genet Test Mol Biomarkers. 2020. PMID: 33181041
Background: Osteoarthritis (OA) is a complex joint disorder characterized by sclerosis of subchondral bone. The knee is one of the most commonly affected joints. Given that the genetic mechanisms underlying knee OA remain elusive, our study aims were to first confirm the a …
Background: Osteoarthritis (OA) is a complex joint disorder characterized by sclerosis of subchondral bone. The knee is one of the mo …
Cisplatin inhibits the proliferation of Saos-2 osteosarcoma cells via the miR-376c/TGFA pathway.
Wang Y, Wu Y, Cai A, Ma C, Cai S, Wang H, Que Y, Xu S, Xu T, Hu Y. Wang Y, et al. Bosn J Basic Med Sci. 2021 Apr 1;21(2):163-173. doi: 10.17305/bjbms.2020.4485. Bosn J Basic Med Sci. 2021. PMID: 32020849 Free PMC article.
Osteosarcoma and normal skeletal muscle tissues were collected from 26 patients by biopsy. TGFA was silenced or overexpressed in Saos-2 osteosarcoma cells by transfection with TGFA-shRNA or TGFA ORF clone, respectively. ...Transfection of Saos-2 cells with …
Osteosarcoma and normal skeletal muscle tissues were collected from 26 patients by biopsy. TGFA was silenced or overexpressed in Saos …
Growth factors and gene expression of stem cells: bone marrow compared with peripheral blood.
Smiler DG, Soltan M, Soltan C, Matthews C. Smiler DG, et al. Implant Dent. 2010 Jun;19(3):229-40. doi: 10.1097/ID.0b013e3181dc24a9. Implant Dent. 2010. PMID: 20523179
Vascular endothelial growth factor alpha is expressed slightly greater in BM and vascular endothelial growth factor beta is slightly more prominent in PB. Transforming growth factors (TGFs) TGFA, TGFB1, and TGFB3 were equally expressed in BM and PB, and TGFB2 had a greater …
Vascular endothelial growth factor alpha is expressed slightly greater in BM and vascular endothelial growth factor beta is slightly more pr …
EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis.
Li L, Ameri AH, Wang S, Jansson KH, Casey OM, Yang Q, Beshiri ML, Fang L, Lake RG, Agarwal S, Alilin AN, Xu W, Yin J, Kelly K. Li L, et al. Oncogene. 2019 Aug;38(35):6241-6255. doi: 10.1038/s41388-019-0873-8. Epub 2019 Jul 16. Oncogene. 2019. PMID: 31312026 Free PMC article.
Despite this, the impact of EGR1 on PC metastatic colonization is unclear. We demonstrate using a PC model (DU145/RasB1) of bone and brain metastasis that EGR1 expression regulates angiogenic and osteoclastogenic properties of metastases. ...Decreased EGR1 expression led t …
Despite this, the impact of EGR1 on PC metastatic colonization is unclear. We demonstrate using a PC model (DU145/RasB1) of bone and …
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance.
Siu MK, Abou-Kheir W, Yin JJ, Chang YS, Barrett B, Suau F, Casey O, Chen WY, Fang L, Hynes P, Hsieh YY, Liu YN, Huang J, Kelly K. Siu MK, et al. Oncotarget. 2014 Jun 15;5(11):3770-84. doi: 10.18632/oncotarget.1994. Oncotarget. 2014. PMID: 25004126 Free PMC article.
Here we show that ectopic miR-203 expression displayed reduced bone metastasis and induced sensitivity to tyrosine kinase inhibitors (TKIs) treatment in a xenograft model. Our results demonstrate that the induction of bone metastasis and TKI resistance require miR-2 …
Here we show that ectopic miR-203 expression displayed reduced bone metastasis and induced sensitivity to tyrosine kinase inhibitors …
Anabolic phenotype in cartilage-specific mitogen-inducible gene-6 knockout mice is independent of transforming growth factor-α.
Hadzic E, To B, Pest MA, Qin L, Beier F. Hadzic E, et al. Osteoarthr Cartil Open. 2023 Jul 26;5(3):100387. doi: 10.1016/j.ocarto.2023.100387. eCollection 2023 Sep. Osteoarthr Cartil Open. 2023. PMID: 37547183 Free PMC article.
METHODS: We generated double knockout mice by crossing cartilage-specific Mig-6(fl/fl)Col2a1-Cre(+/-) and whole-body Tgfa() mice to generate experimental and control wild-type mice. ...Similarly, articular cartilage cell density is increased in Mig6-cKO/Tgfa-KO and …
METHODS: We generated double knockout mice by crossing cartilage-specific Mig-6(fl/fl)Col2a1-Cre(+/-) and whole-body Tgfa() mice to g …
Interaction Effect of RsaI and BamHI Polymorphisms of TGFα, BMP2 and BMP4 on the Occurrence of Non-Syndromic Cleft Lip and Palate in Iranian Patients.
Samadi S, Ebadifar A, Khorram Khorshid HR, Kamali K, Badiee M. Samadi S, et al. Avicenna J Med Biotechnol. 2018 Oct-Dec;10(4):248-252. Avicenna J Med Biotechnol. 2018. PMID: 30555658 Free PMC article.
This study aimed to assess the interaction effect of Rsal and BamHI polymorphisms of Transforming Growth Factor-alpha (TGFalpha) gene and Bone Morphogenetic Protein-2 (BMP2) and BMP4 variants on the occurrence of Non-Syndromic Cleft Lip and Palate (NSCLP) in the Iranian po …
This study aimed to assess the interaction effect of Rsal and BamHI polymorphisms of Transforming Growth Factor-alpha (TGFalpha) gene and …
TGFα expression in myeloid malignancies.
Kavanagh S, Mirzai B, Fuller K, Erber WN. Kavanagh S, et al. J Clin Pathol. 2016 Jun;69(6):543-6. doi: 10.1136/jclinpath-2015-203526. Epub 2016 Mar 16. J Clin Pathol. 2016. PMID: 26984929 Free PMC article.
METHODS: TGFalpha expression was semiquantitatively assessed in 69 normal bone marrow trephines and 157 cases of myeloid malignancy using an immunohistochemical approach. ...
METHODS: TGFalpha expression was semiquantitatively assessed in 69 normal bone marrow trephines and 157 cases of myeloid malignancy u …
Comparative Evaluation of Different Bone Markers in Peri-implant Crevicular Fluid of Immediate Loaded and Nonloaded Dental Implants.
Haque MIU, Sharma P, Tiwari A, Subhas S, Rana M, Kumar V. Haque MIU, et al. J Contemp Dent Pract. 2018 Nov 1;19(11):1341-1345. J Contemp Dent Pract. 2018. PMID: 30602638
RESULTS: Both groups revealed non-significant difference in modified bleeding on probing index and peri-implant sulcus depth (p > 0.05). Bone markers found to be elevated more in group I as compared to group II. ...CLINICAL SIGNIFICANCE: Immediate loaded dental implants …
RESULTS: Both groups revealed non-significant difference in modified bleeding on probing index and peri-implant sulcus depth (p > 0.05). …
IL-1beta-mediated NF-kappaB signaling augments the osteosarcoma cell growth through modulating miR-376c/TGFA axis.
Liu B, Zhou Y, Chen X, Peng D. Liu B, et al. Pharmazie. 2017 Jul 3;72(7):419-424. doi: 10.1691/ph.2017.6888. Pharmazie. 2017. PMID: 29441940
In our previous study, we reported that miR-376c inhibited the growth of osteosarcoma (OS) cells by targeting TGFA. Here, we revealed that miR-376c was downregulated in OS tissues and cells while IL-1beta, NF-kappaB and TGFA were upregulated in OS tissues and cells. …
In our previous study, we reported that miR-376c inhibited the growth of osteosarcoma (OS) cells by targeting TGFA. Here, we revealed …
27 results